Thomas Kahan Selected Research

Irbesartan

12/2013	Markers of inflammation, endothelial activation, and arterial stiffness in hypertensive heart disease and the effects of treatment: results from the SILVHIA study.
8/2009	The effects of antihypertensive treatment on the doppler-derived myocardial performance index in patients with hypertensive left ventricular hypertrophy: results from the Swedish irbesartan in left ventricular hypertrophy investigation versus atenolol (SILVHIA).
7/2008	The relationship between the plasma concentration of irbesartan and the antihypertensive response is disclosed by an angiotensin II type 1 receptor polymorphism: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs. Atenolol (SILVHIA) Trial.
9/2007	Myocardial fibrosis and diastolic dysfunction in patients with hypertension: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA).
9/2006	Tissue velocity echocardiography shows early improvement in diastolic function with irbesartan and atenolol therapy in patients with hypertensive left ventricular hypertrophy. Results form the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA).
3/2005	Irbesartan and atenolol improve diastolic function in patients with hypertensive left ventricular hypertrophy.
12/2004	Single nucleotide polymorphisms predict the change in left ventricular mass in response to antihypertensive treatment.
3/2004	Transforming growth factor beta1 genotype and change in left ventricular mass during antihypertensive treatment--results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA).
1/2004	Angiotensinogen gene polymorphisms: relationship to blood pressure response to antihypertensive treatment. Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial.
12/2003	Long-term effects of irbesartan and atenolol on the renin-angiotensin-aldosterone system in human primary hypertension: the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA).

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Thomas Kahan Research Topics

Disease

29	Hypertension (High Blood Pressure) 01/2021 - 08/2002
17	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 06/2010 - 04/2002
12	Essential Hypertension 08/2009 - 04/2002
9	Heart Failure 01/2021 - 01/2002
8	Hypertrophy 01/2018 - 08/2002
7	Inflammation (Inflammations) 01/2020 - 08/2013
6	Peripheral Arterial Disease 12/2021 - 01/2017
6	Atrial Fibrillation 01/2021 - 10/2014
5	Cardiovascular Diseases (Cardiovascular Disease) 12/2022 - 08/2002
4	Stroke (Strokes) 01/2021 - 03/2002
4	Fibrosis (Cirrhosis) 01/2020 - 03/2004
4	Myocardial Infarction 01/2020 - 05/2003
3	Insulin Resistance 01/2022 - 12/2003
3	Hyperemia 01/2022 - 10/2008
3	Familial Combined Hyperlipidemia (Combined Hyperlipidemia, Familial) 10/2021 - 10/2008
3	Pre-Eclampsia (Preeclampsia) 11/2020 - 06/2010
3	Coronary Disease (Coronary Heart Disease) 01/2018 - 02/2005
3	Stable Angina 09/2013 - 03/2009
2	Hemorrhage 12/2021 - 11/2021
2	Diabetes Mellitus 01/2018 - 06/2010
2	Systolic Heart Failure 10/2014 - 06/2014
2	Cardiomegaly (Heart Hypertrophy) 12/2013 - 12/2003
2	Necrosis 12/2013 - 08/2013
2	Angina Pectoris 02/2013 - 02/2004
2	Premature Birth (Birth, Premature) 06/2010 - 06/2007
2	Asthma (Bronchial Asthma) 06/2010 - 06/2007
2	Jaundice (Icterus) 06/2010 - 06/2007
2	Pneumonia (Pneumonitis) 06/2010 - 06/2007
2	Sepsis (Septicemia) 06/2010 - 06/2007
2	Reperfusion Injury 01/2004 - 05/2003
1	Atherosclerosis 12/2021
1	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 10/2021
1	Body Weight (Weight, Body) 01/2021
1	Fatigue 01/2021
1	Type 2 Diabetes Mellitus (MODY) 01/2021
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2021
1	Acute Coronary Syndrome 01/2021
1	Chest Pain (Chest Pains) 01/2021
1	Hypertensive Crisis 11/2020
1	Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced) 11/2020
1	Disease Progression 01/2020

Drug/Important Bio-Agent (IBA)

20	Atenolol (Tenormin)FDA LinkGeneric 12/2013 - 04/2002
18	Antihypertensive Agents (Antihypertensives)IBA 12/2022 - 04/2002
17	Irbesartan FDA LinkGeneric 12/2013 - 04/2002
11	Angiotensin IIIBA 10/2021 - 05/2002
9	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2021 - 08/2002
8	LipidsIBA 12/2021 - 02/2005
7	Pharmaceutical PreparationsIBA 01/2021 - 11/2013
7	Angiotensin Receptor AntagonistsIBA 01/2021 - 12/2013
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 06/2014
4	Ramipril (Altace)FDA LinkGeneric 03/2019 - 08/2002
3	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 12/2013
3	Insulin (Novolin)FDA Link 01/2020 - 12/2003
3	Doxazosin (Cardura)FDA LinkGeneric 03/2019 - 06/2017
3	CollagenIBA 01/2017 - 09/2007
3	C-Reactive ProteinIBA 01/2016 - 08/2013
3	Collagen Type I (Type I Collagen)IBA 10/2014 - 09/2007
3	Adenosine (Adenocard)FDA LinkGeneric 12/2005 - 05/2003
2	CholesterolIBA 01/2022 - 04/2015
2	Triglycerides (Triacylglycerol)IBA 01/2022 - 04/2015
2	RivaroxabanIBA 12/2021 - 11/2021
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/2021 - 11/2021
2	AngiotensinsIBA 10/2021 - 01/2016
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2018 - 08/2002
2	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2017 - 06/2014
2	Thrombin FDA Link 06/2015 - 08/2002
2	Interleukin-6 (Interleukin 6)IBA 12/2013 - 08/2013
2	E-SelectinIBA 12/2013 - 08/2002
2	IvabradineIBA 09/2013 - 03/2009
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 08/2013 - 08/2002
2	Atorvastatin (Lipitor)FDA Link 01/2009 - 02/2005
2	Amlodipine (Norvasc)FDA LinkGeneric 01/2009 - 01/2007
2	Type 1 Angiotensin ReceptorIBA 07/2008 - 04/2002
2	Angiotensin II Type 1 Receptor BlockersIBA 12/2004 - 01/2004
1	HDL-triglycerideIBA 01/2022
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2022
1	Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric 01/2022
1	TabletsIBA 01/2021
1	Spironolactone (Aldactone)FDA LinkGeneric 01/2021
1	SodiumIBA 01/2021
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 01/2021
1	finerenoneIBA 01/2021
1	AnticoagulantsIBA 01/2021
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2021
1	Exenatide (Byetta)FDA Link 01/2021
1	Neprilysin (Neutral Endopeptidase)IBA 01/2021
1	MelatoninIBA 01/2020
1	TroponinIBA 01/2020
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2020
1	ResveratrolIBA 01/2020
1	MagnesiumIBA 01/2020

Therapy/Procedure

13	Therapeutics 12/2021 - 04/2002
4	Vascular Surgical Procedures 02/2018 - 01/2017
3	Lasers (Laser) 01/2022 - 10/2008
2	Denervation 01/2018 - 01/2014
2	Intravenous Infusions 06/2015 - 10/2008
2	Cesarean Section (Caesarean Section) 06/2010 - 06/2007
2	Phototherapy (Light Therapy) 06/2010 - 06/2007
1	Glycemic Control 01/2021
1	Analgesia 11/2020